Table 10 Correlation of the developmental defect with resultant abnormality and possible clinical consequence

Abnormal insertion and migration of the orifice of the mesonephric duct

Posterior urethral valve

Obstructive uropathy

Abnormal development and absorption of the ‘Common excretory duct’

Defective development of the ipsilateral hemitrigone

Abnormal “uretero-trigonal” mechanism with a neuromuscular defect and abnormal vesicoureteric junction (VUJ)

Abnormality in the position of the ureteral bud and its development from the mesonephric duct

Defect in the entire collecting system, from the ureter to collecting tubules

VUR and reflux nephropthy; ureteric obstruction; hydroureteronephrosis; megaureter

Abnormal induction of the metanephric blastema by the ureteral bud

Maldevelopment of the kidney

Inherent renal dysplasia