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Table 2 BTI to treat CIH: doses and dillutions

From: Botulinum toxin abdominal wall injection and post-omphalocele ventral hernia repair: database and proposal of a protocol

Author Total/case Total/injection Number of injections Dillution
Ibarra-Hurtado et al. 2009 [17] 500 IU disport 50 IU/0.5 ml 5/ side 100 IU/ml
Ibarra-Hurtado et al. 2014 [13] 500 IU disport 50 IU/0.5 ml 5/ side 100 IU/ml
Elstner et al. 2016 [9] 300 IU botox 16 IU/8 ml 3/side 2 IU/ml
Chavez-Tostado et al. 2014 [7] 100 IU Botox 10 IU/0.2 ml 5/side 50 IU/ml
Rodriguez-Acevedo et al. 2018a [4] 200-300 IU botoxb 16 IU/8 ml 3/side 2 IU/ml
Nielsen et al. 2019 [12] 300 IU botox 30 IU/6–15 ml 5/side 2–5 IU/ml
Zielinski et al. 2013 [14] 300 IU botox 17 UI/8 ml 3/side 2 UI/ml
  1. aSelective association of PPP (> 15 cm defect, infraumbilical >9 cm defect, hernia volume/abdominal volume > 20%)
  2. bSimilar results in 200 and 300 IU groups