Botulinum toxin abdominal wall injection and post-omphalocele ventral hernia repair: database and proposal of a protocol

Annals of Pediatric Surgery

Table 2 BTI to treat CIH: doses and dillutions

Author	Total/case	Total/injection	Number of injections	Dillution
Ibarra-Hurtado et al. 2009 [17]	500 IU disport	50 IU/0.5 ml	5/ side	100 IU/ml
Ibarra-Hurtado et al. 2014 [13]	500 IU disport	50 IU/0.5 ml	5/ side	100 IU/ml
Elstner et al. 2016 [9]	300 IU botox	16 IU/8 ml	3/side	2 IU/ml
Chavez-Tostado et al. 2014 [7]	100 IU Botox	10 IU/0.2 ml	5/side	50 IU/ml
Rodriguez-Acevedo et al. 2018^a [4]	200-300 IU botox^b	16 IU/8 ml	3/side	2 IU/ml
Nielsen et al. 2019 [12]	300 IU botox	30 IU/6–15 ml	5/side	2–5 IU/ml
Zielinski et al. 2013 [14]	300 IU botox	17 UI/8 ml	3/side	2 UI/ml

^aSelective association of PPP (> 15 cm defect, infraumbilical >9 cm defect, hernia volume/abdominal volume > 20%)
^bSimilar results in 200 and 300 IU groups