Fig. 1
From: Mixed cortico-medullary adrenal carcinoma in children: looks are deceptive!!
A CECT abdomen shows a suprarenal heterogeneous mass with stippled calcification encasing major vessels. B Cellular fragments showing large atypical cells having moderate cytoplasm, pleomorphic nuclei and prominent nucleoli forming acini. (Giemsa, 400X). Inset: Melan A positive tumor cells (Immunocytochemistry, 400X, DAB as chromogen). C Adrenal mass showing solid, variegated lesion with large areas of necrosis and haemorrhage. D Microscopy shows a viable malignant tumor with geographical areas of necrosis, E Tumor cells forming rosettes (Hematoxylin & Eosin, 100X), F Reviewed cytology smears showing two population of cells (Giemsa, 400X)