Table 2 Patient characteristics for off ECMO repair v. on ECMO repair. Off ECMO repair patients were less likely to have an intrathoracic liver and had a higher median PPLV than those repaired on ECMO. Data is presented as median (IQR) or as a percentage
Variable | Off ECMO repaira | On ECMO repairb | P-value |
|---|---|---|---|
Assigned female at birth | 4/6 (66.7%) | 23/48 (47.9%) | 0.6687 |
Caucasian | 6/6 (100%) | 31/48 (60.4%) | 0.1607 |
Birth weight (kg) | 3.1 (2.8–3.4) | 3.0 (2.5–3.0) | 0.3573 |
Gestational age at birth | 38 (37.3–38) | 38 (37–38) | 0.5882 |
Congenital heart defect | 0/6 (0%) | 6/48 (12.5%) | >0.9999 |
C-section delivery | 2/6 (33.3%) | 28/48 (58.3%) | 0.3890 |
1-min APGAR | 2.5 (1–7) | 3 (1.5–5) (n = 35) | 0.9036 |
5-min APGAR | 6.5 (6–8) | 5 (4.25–7) (n = 35) | 0.2743 |
pH at birth | 7.11 (7.05–7.11) (n = 4) | 7.02 (6.95–7.14) (n = 46) | 0.4294 |
Day of life ECMO started | 1.0 (1.0–1.75) | 1.0 (1.0–1.0) | 0.4037 |
Day of life repaired | 11 (8.25–16) | 3 (2–6) | 0.0002 |
Left-sided hernia | 6/6 (100%) | 33/48 (68.8%) | 0.1702 |
Intrathoracic liver | 2/6 (33.3%) | 46/48 (95.8%) | 0.0007 |
Prenatally diagnosed | 6/6 (100%) | 40/48 (83.3%) | 0.5754 |
Prenatal imaging | |||
LHR (US) | 1.3 (1.2–1.3) (n = 3) | 1.0 (0.7–1.2) (n = 29) | 0.0971 |
O/E LHR (US) | 57.8 (57.8–57.8) (n = 1) | 34.8 (23.1–42.4) (n = 30) | n/a |
TLV (MRI) | 18.4 (13.5–26.9) (n = 3) | 20.3 (13.8–42.4) (n = 35) | 0.9595 |
PPLV (MRI) | 21.7 (20.4–22.9) (n = 3) | 14.3 (12–16.9) (n = 34) | 0.0131 |